Good question. I guess it really depends on the situation. If it's a house in the suburbs, with lots of neighbors around (unless they're all aliens or bloodsucking mutants of some sort), then there's a general degree of safety and protection to be felt. But if it's some ranch house or farmhouse in the middle of BFE, that adds some discomfort and imagination.
The woods for me, though. Much as I love spending time in nature, it makes you really vulnerable. I got dragged to a few parties in the woods as a teenager, and I remember thinking that some mutated, unkillable dude could pop up out of nowhere with a machete and brutally murder all the underage drinkers and fornicators and no one would ever see it coming. Seemed likely and favorable to me.
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