I never made it through "Seed" by Uwe Bol, but for different reasons. There was a subtitle meltdown, however, from what I've read it's pretty nasty anyway (although from what I saw it's also totally unrealistic!). It does have scenes of genuine animal cruelty in the first five minutes (although these were not filmed specially for Seed but were existing footage).
I agree Men Behind the Sun is very difficult to watch, as is August and Cannibal Holocaust. Also, a short called Cutting Moments. Very effective!
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