*Carmilla by Joseph Sheridan Le Fanu
*The Vampyre by John Polidori
*The Strange Case of Dr Jekyll and Mr Hyde by Robert Louis Stevenson
*The Hellbound Heart by Clive Barker
*The Firestarter by Stephen King
*The Stand by Stephen King
*Varney the Vampire by James Malcolm Rymer (Sometimes attributed to Thomas Preskett Prest)
*Interview with a Vampire by Anne Rice
*The Day of the Triffids by John Wyndham
*Cell Stephen King

Ten's tough. Some great picks already and a couple more I've been meaning to get to. Not much eye-rolling yet although I assume Doc included Ulysses because it gave him nightmares in school. It sure gave me some sleepless nights. And I still wake up screaming thinking I'm back at chapter one again. Anyway, here's my ten of the moment.

The Island of Dr Moreau - Wells
Dracula - Stoker
Frankenstein - Shelly
Salem's Lot - King
The Mask of the Red Death - Poe
A Christmas Carol - Dickens
Rebecca - Du Maurier
Moonchild - Crowley
House of Seven Gables - Hawthorne
The Metamorphosis - Kafka

Outside of Lovecraft/Mr James ect I'm not a big Horror reader and most of these are short stories but I'll try do a top 10.

Read the brothel sequence again. And I call a man in a long black coat presaging weird shit about to go down a horror element.

Ok in no particular order (and some are Collections/short stories/Novellas) and I bet I missed alot - I also limited one per Author:

1) A Clockwork Orange - Anthoney Burgess
2) Ghost Stories of an Antiquary - MR JAMES
3) The Shadow over Innsmouth - HP Lovecraft
4) Adrift on The Haunted Seas - William Hope Hodgson
5) The Adventure of the Sussex Vampire - Sir Arthur Conan Doyle
6) The Anno Dracula Series - Kim Newman
7) Draqcula - Bram Stoker
8) Masque of the Red Death - E.A Poe
9) Books of Blood series - Clive Barker
10) I Am Legend - Richard Matheson
11) Blood Meridian

Thanks to everyone thus far. I'm seeing some great stuff.

I thought we where supposed to mention things that where not already mentioned, if we can mention the same as others then off course both Dracula by Bram Stoker and Frankenstein by Mary Shelly have to be on my list, you can not have a list over the most influential horror books and not mention these two.

The more stuff the better. It's best to get a large sampling then reduce it to 100.

Trying to spotlight a few things not mentioned by others, as well as mention collections for short story writers.

Something Wicked This Way Comes - Ray Bradbury
Tales of Terror & Darkness - Algernon Blackwood
Complete Stories and Poems of Edgar Allan Poe
H. P. Lovecraft: Tales (Library of America)
The Wolfen - Whitley Strieber
The Turn of the Screw - Henry James
The Other - Tom Tryon
Sheridan Le Fanu - Carmilla
The Hounds of Tindalos - Frank Belknap Long
I Am Legend - Richard Matheson

I'll be the first to break the rule and list an 11th:

Moby Dick - Herman Melville